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Updated: May 27, 2026
09:16
A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells
Published on: June 10, 2015
A quarter century of granzymes
C L Ewen1, K P Kane, R C Bleackley
1Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.
Cell Death and Differentiation
|November 5, 2011
Abstract:
Granzymes (Grs) were discovered just over a quarter century ago. They are produced by cytotoxic T cells and natural killer cells and are released upon interaction with target cells. Intensive biochemical, genetic, and biological studies have been performed in order to study their roles in immunity and inflammation. This review summarizes research on the family of Grs.
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