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Pyrazole sulfanilamides: nitroderivatives of 1-phenyl-3-sulfanilamidopyrazole. Note XVI
C Tironi1, R Fruttero, A Garrone
1Dipartimento di Scienza e Tecnologia del Farmaco, Torino, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1990
Abstract:
Synthesis and structural characterization of 3 sulfanilamido-1-phenylpyrazoles bearing on 1-phenyl group nitro substituent o-, m-, p-positioned are reported. All derivatives are analysed through 1H and 13C NMR spectroscopy. The MIC values obtained against Escherichia coli are briefly discussed in terms of structure-activity relationship.