Related Experiment Videos
[Two cases of brain infarction associated with hypertriglyceridemia]
H Yamanouchi1, Y Seki, T Yanagisawa
1Department of Pediatrics, Tone Central Hospital, Numata.
No to Hattatsu = Brain and Development
|July 1, 1990
Summary
Two young cousins experienced brain infarctions, presenting with distinct neurological deficits. Hypertriglyceridemia was identified as a potential contributing factor in these pediatric stroke cases.
Area of Science:
- Neurology
- Pediatrics
- Radiology
Background:
- Brain infarction, or stroke, is uncommon in children.
- Cousin relationship suggests potential genetic predisposition.
- Hypertriglyceridemia is a known risk factor for cardiovascular events.
Observation:
- Case 1: A 12-year-old girl presented with aphasia, dyscalculia, disorientation, and hemianopsia.
- Case 2: A 15-year-old boy exhibited hemiplegia and sensory deficits.
- Cerebral computed tomography (CT) revealed distinct low-density areas in both patients, indicating infarction.
Findings:
- Case 1 infarction localized to the left temporal lobe, correlating with language and visual deficits.
- Case 2 infarction involved the right internal capsule and putamen, consistent with motor and sensory impairments.
- Both patients shared hypertriglyceridemia, suggesting its potential role in the etiology of these pediatric brain infarctions.
Implications:
- Highlights the importance of considering hypertriglyceridemia in pediatric stroke evaluations.
- Suggests potential genetic or familial factors contributing to stroke risk in adolescents.
- Emphasizes the need for early diagnosis and management of dyslipidemia in children to prevent cerebrovascular events.