Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recurrent pericarditis. Relief with colchicine.

J Guindo1, A Rodriguez de la Serna, J Ramió

  • 1Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Spain.

Circulation
|October 1, 1990
PubMed
Summary

Colchicine effectively prevents pericarditis recurrence in patients with multiple relapses. This treatment allowed discontinuation of prednisone and maintained symptom-free periods, suggesting colchicine

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Management of heart failure in cardiology and primary care (MICCAP) program: Improving the management of patients with heart failure].

Semergen·2018
Same author

Comments on the 2015 ESC Guidelines for the Diagnosis and Management of Pericardial Diseases. A Report by the Spanish Society of Cardiology Guidelines Committee Working Group.

Revista espanola de cardiologia (English ed.)·2015
Same author

Advanced interatrial block as a substrate of supraventricular tachyarrhythmias: a well recognized syndrome.

Journal of electrocardiology·2015
Same author

IL28RA polymorphism is associated with early hepatitis C virus (HCV) treatment failure in human immunodeficiency virus-/HCV-coinfected patients.

Journal of viral hepatitis·2013
Same author

Association of torque teno virus (TTV) and torque teno mini virus (TTMV) with liver disease among patients coinfected with human immunodeficiency virus and hepatitis C virus.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2012
Same author

Use of transient elastography (FibroScan®) for the noninvasive assessment of portal hypertension in HIV/HCV-coinfected patients.

Journal of viral hepatitis·2011

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Recurrence of pericarditis is a significant clinical challenge.
  • Current treatments for recurrent pericarditis often involve immunosuppressants or surgery.
  • Patients frequently experience multiple relapses despite standard therapies.

Purpose of the Study:

  • To evaluate the efficacy of colchicine in preventing pericarditis recurrence.
  • To assess colchicine's role in patients with refractory or recurrent pericarditis.

Main Methods:

  • An open-label prospective study involving nine patients with a history of at least three pericarditis relapses.
  • Patients received colchicine (1 mg/day) for recurrence prevention.
  • Statistical analysis used a paired comparison design (Student's t test).

Related Experiment Videos

Main Results:

  • All nine patients responded favorably to colchicine therapy.
  • Prednisone was successfully discontinued in all patients within 2-6 weeks.
  • No recurrences were observed during a mean follow-up of 24.3 months (range, 10-54 months).
  • A statistically significant improvement in symptom-free periods was noted (p < 0.002).

Conclusions:

  • Colchicine appears to be a promising agent for preventing pericarditis recurrence.
  • The findings suggest colchicine can facilitate the withdrawal of other medications like prednisone.
  • Larger, double-blind studies are warranted to confirm these results.