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Related Experiment Video

Updated: May 27, 2026

Isolation and Characterization of the Natural Microbiota of the Model Nematode Caenorhabditis elegans
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Isolation and Characterization of the Natural Microbiota of the Model Nematode Caenorhabditis elegans

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Networks in Caenorhabditis elegans.

Kristin C Gunsalus1, Kahn Rhrissorrakrai

  • 1Center for Genomics and Systems Biology and Department of Biology, New York University, 12 Waverly Place, 8th floor, New York, NY 10012, USA. kcg1@nyu.edu

Current Opinion in Genetics & Development
|November 8, 2011
PubMed
Summary

This review explores molecular interaction networks in Caenorhabditis elegans, highlighting how analyzing gene and protein connections reveals biological functions and system properties.

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Area of Science:

  • Systems Biology
  • Genomics
  • Developmental Biology

Background:

  • The network paradigm is crucial in modern biology, utilizing large functional genomic datasets to understand gene, transcript, and protein interactions.
  • Molecular interaction networks reveal global architecture and local connectivity patterns, underpinning functional properties like robustness and modularity.

Purpose of the Study:

  • To review recent advancements in elucidating molecular interaction networks.
  • To illustrate current directions in network biology using functional assays in Caenorhabditis elegans.

Main Methods:

  • Analysis of functional genomic datasets.
  • Application of various functional assays.
  • Utilizing Caenorhabditis elegans as a model organism for animal development.

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Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons
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Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons

Published on: September 7, 2017

Basic Caenorhabditis elegans Methods: Synchronization and Observation
11:34

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Published on: June 10, 2012

Related Experiment Videos

Last Updated: May 27, 2026

Isolation and Characterization of the Natural Microbiota of the Model Nematode Caenorhabditis elegans
07:05

Isolation and Characterization of the Natural Microbiota of the Model Nematode Caenorhabditis elegans

Published on: August 17, 2022

Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons
07:31

Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons

Published on: September 7, 2017

Basic Caenorhabditis elegans Methods: Synchronization and Observation
11:34

Basic Caenorhabditis elegans Methods: Synchronization and Observation

Published on: June 10, 2012

Main Results:

  • Demonstration of how network structure relates to functional properties (e.g., robustness, modularity, feedback loops).
  • Examples of network elucidation in Caenorhabditis elegans.

Conclusions:

  • Molecular interaction networks are key to understanding biological complexity.
  • Caenorhabditis elegans serves as a valuable model for network biology research.