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Transgenic rice accumulating modified cedar pollen allergen Cry j 2 derivatives

Kazuya Suzuki¹, Lijun Yang, Fumio Takaiwa

¹Functional Crop Research and Development Unit, National Institute of Agrobiological Science, 2-1-2 Kannondai, Tsukuba, Ibaraki 305-8602, Japan.

Journal of Bioscience and Bioengineering

|November 8, 2011

Abstract:

In order to create a safe tolerogenic antigen with reduced IgE reactivity, we developed transgenic rice that accumulates in the seed endosperm a sufficient amount of Cry j 2, the cedar pollen allergen, in a restructured form of tail-to-head, providing a feasible mucosal allergy vaccine against cedar pollinosis.

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