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Genetics of maximally attained lung function: a role for leptin?

Bram van den Borst1, Nicole Y P Souren, Ruth J F Loos

  • 1Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands. b.vdborst@maastrichtuniversity.nl

Respiratory Medicine
|November 8, 2011
PubMed
Summary

Genetic factors significantly influence maximal lung function, explaining over 60% of variation in forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC). Leptin may also play a role in achieving peak lung capacity.

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