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Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
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[Nail involvement in leprosy].

I Belinchón Romero1, J M Ramos Rincón, F Reyes Rabell

  • 1Sección de Dermatología, Hospital General Universitario de Alicante, España. belinchon isa@gva.es

Actas Dermo-Sifiliograficas
|November 8, 2011
PubMed
Summary
This summary is machine-generated.

Leprosy significantly impacts nails in most patients, causing diverse changes like onycholysis and nail deformities due to nerve damage and trauma. Understanding these nail manifestations is crucial for comprehensive leprosy management.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Nail Medicine

Context:

  • Leprosy, caused by Mycobacterium leprae, is a chronic infectious disease primarily affecting skin and peripheral nerves.
  • Nail involvement is highly prevalent, occurring in up to 75% of leprosy patients.
  • Nail changes are often overlooked but are significant indicators of disease morbidity.

Purpose:

  • To comprehensively review and describe the principal nail changes associated with leprosy.
  • To elucidate the diverse etiologies behind these nail alterations, including trauma, neuropathy, and treatment-related factors.
  • To highlight the diagnostic and prognostic significance of nail manifestations in leprosy.

Summary:

  • Leprosy frequently causes a wide spectrum of nail changes, such as subungual hematomas, onycholysis, onychauxis, onychogryphosis, and pterygium unguis.
  • Neuropathy, vascular impairment, infections, lepra reactions, and medications contribute to these nail abnormalities.
  • Advanced stages may exhibit acro-osteolysis-related changes like brachyonychia or anonychia, alongside infections like paronychia and onychomycosis.

Impact:

  • Recognizing these varied nail changes aids in the early diagnosis and comprehensive management of leprosy.
  • Understanding the link between leprosy and nail pathology can improve patient care and reduce long-term morbidity.
  • This review emphasizes the importance of dermatological examination, including nail assessment, in leprosy patients.