Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preliminary Evaluation of 225Ac/177Lu-DOTATATE PRRT in Progressive Meningiomas: Efficacy, Dosimetry, and Imaging Insights.

Clinical nuclear medicine·2026
Same author

Quantitative <sup>99m</sup>Tc-PYP SPECT/CT at 90 minutes improves diagnostic stratification in transthyretin cardiac amyloidosis.

European journal of nuclear medicine and molecular imaging·2026
Same author

Diagnostic Performance of FAPI PET in Patients with Breast Cancer: A Systematic Review.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Late post-treatment 131I SPECT/CT reveals additional lymph node metastasis of papillary thyroid carcinoma.

Nuklearmedizin. Nuclear medicine·2026
Same author

Prospective Head-to-Head Comparison of Fibroblast Imaging with [<sup>68</sup>Ga]Ga-FAPI-46 PET/CT and [<sup>18</sup>F]FDG PET/CT in Unclear Hepatic Lesions.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Multidisciplinary management of meningiomas in the era of precision oncology.

Nature reviews. Clinical oncology·2026

Related Experiment Video

Updated: May 27, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

I-131-MIBG therapies.

Stefan Vöö1, Jan Bucerius, Felix M Mottaghy

  • 1Department of Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands. stefan.voo@mumc.nl

Methods (San Diego, Calif.)
|November 8, 2011
PubMed
Summary

Metaiodobenzylguanidine (MIBG) therapy uses I-131-MIBG to treat neuroendocrine tumors. This overview details how to perform this molecular nuclear therapy for conditions like neuroblastoma and pheochromocytoma.

Area of Science:

  • Nuclear medicine
  • Oncology
  • Radiopharmacology

Background:

  • Metaiodobenzylguanidine (MIBG) is a tracer that selectively targets neuroendocrine cells.
  • Radiolabeled iodinated-MIBG (I-131-MIBG) is utilized for molecular nuclear therapy.
  • Neuroendocrine tumors (NETs) are a diverse group of neoplasms.

Purpose of the Study:

  • To provide an overview of I-131-MIBG therapy for neuroendocrine tumors.
  • To focus on the practical aspects of performing I-131-MIBG treatment.
  • To consolidate existing knowledge on I-131-MIBG therapy protocols.

Main Methods:

  • Review of existing literature on I-131-MIBG therapy.
  • Analysis of therapeutic doses and schemes.
  • Discussion of treatment protocols and efficiency.

More Related Videos

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

Related Experiment Videos

Last Updated: May 27, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

Main Results:

  • I-131-MIBG therapy is effective for various NETs, including neuroblastoma, pheochromocytoma, and paraganglioma.
  • Extensive research has optimized doses, therapeutic schemes, and assessed efficiency.
  • The paper offers insights into the procedural aspects of administering I-131-MIBG therapy.

Conclusions:

  • I-131-MIBG therapy is a valuable treatment modality for selected neuroendocrine tumors.
  • Further optimization of therapeutic strategies continues to enhance treatment outcomes.
  • Understanding the performance aspects is crucial for successful clinical application.