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Updated: May 27, 2026

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
Published on: August 4, 2016
Gene expression profiling in adrenocortical neoplasia
G Assie1, T J Giordano, J Bertherat
1INSERM U1016, Institut Cochin, Paris, France. guillaume.assie@cch.aphp.fr
Abstract:
Transcriptome studies of adrenocortical tumors have shown clear differences between adenomas and carcinomas and identified two subgroups of carcinomas with different prognoses. This review focuses on how transcriptomes have enriched our knowledge about genes previously identified by classical candidate gene approaches, uncovered novel genes relevant to adrenocortical tumor biology, helped to identify and understand specific pathway alterations, and advanced the overall translational relevance of this field of research.
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