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Updated: May 27, 2026

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
09:41

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang1, Yan Xia, Haitao Ji

  • 1Brain Tumor Center and Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

Nature
|November 8, 2011
PubMed
Summary

Epidermal growth factor receptor (EGFR) activates pyruvate kinase M2 (PKM2) nuclear translocation, promoting cancer cell proliferation. This highlights PKM2

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