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Related Concept Videos

Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
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Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions
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Obesity, cognitive functioning and dementia: back to the future.

Merrill F Elias1, Amanda L Goodell, Shari R Waldstein

  • 1Department of Psychology, University of Maine, Orono, Maine, USA. MFEliasUmaine@aol.com

Journal of Alzheimer'S Disease : JAD
|November 8, 2011
PubMed
Summary

Chronic obesity and overweight status are linked to cognitive decline and dementia. However, early-life cognitive deficits may also increase body weight, highlighting the need for lifespan research on weight and cognition.

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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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Published on: February 14, 2014

Area of Science:

  • Neuroscience
  • Public Health
  • Gerontology

Background:

  • Chronic obesity and overweight status are established risk factors for cognitive decline, dementia, and impaired cognitive performance.
  • Emerging evidence suggests that lower cognitive performance early in life may predict future increases in body weight.

Purpose of the Study:

  • To review literature on the relationship between body weight and cognitive functioning.
  • To highlight methodological and theoretical advancements in understanding weight-cognition links.
  • To examine the evolution of research from focusing on cardiovascular factors to metabolic, lifestyle, and genetic mechanisms.

Main Methods:

  • Literature review focusing on studies examining the bidirectional relationship between weight and cognition.
  • Analysis of research evolution from dementia diagnosis backward to pre-clinical stages.
  • Examination of shifting emphasis from cardiovascular risk factors to metabolic, lifestyle, and genetic mediators.

Main Results:

  • Research has evolved to explore pre-clinical stages of dementia and a broader range of mediating factors beyond cardiovascular risks.
  • Understanding the causal links requires a lifespan perspective, integrating research across different life stages.
  • Reciprocal relationships between weight and cognition, particularly in early life, require further investigation.

Conclusions:

  • A comprehensive understanding of weight-cognition dynamics necessitates a lifespan approach.
  • Integrating research across life segments is crucial for a holistic view of weight and cognition.
  • Future research should prioritize studies examining the bidirectional influence of weight and cognition throughout life, especially during early development.