Related Experiment Video

Updated: May 27, 2026

Murine Kidney Transplant Technique
08:58

Murine Kidney Transplant Technique

Published on: October 20, 2015

Urinary tract infection after kidney transplantation in children and adolescents

Mohammad Kazem Fallahzadeh1, Mohammad Hossein Fallahzadeh, Ali Derakhshan

  • 1Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Kazem.fa@gmail.com.

Iranian Journal of Kidney Diseases
|November 8, 2011
PubMed

Insights

Urinary tract infections (UTIs) are common after pediatric kidney transplants. Female gender and neurogenic bladder are significant risk factors for UTIs in these young patients.

Area of Science:

  • Pediatric Nephrology
  • Transplantation Immunology
  • Urology

Background:

  • Urinary tract infections (UTIs) represent a significant post-transplant complication in pediatric kidney recipients.
  • Identifying UTI prevalence and risk factors is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To determine the incidence of UTIs in children and adolescents following kidney transplantation.
  • To investigate associated risk factors for UTI development in this vulnerable population.

Main Methods:

  • Retrospective analysis of pediatric kidney transplant recipients (under 19 years) from 1992-2008.
  • Review of confirmed UTI episodes occurring after the first month post-transplantation.
  • Evaluation of patient demographics, primary kidney disease, and bladder conditions.

Main Results:

  • Urinary tract infection (UTI) was documented in 24 out of 138 pediatric kidney transplant recipients (17.4%).
  • Female gender and neurogenic bladder were identified as significant risk factors for UTI.
  • Patients with neurogenic bladder experienced recurrent UTIs despite prophylactic antibiotics.

Conclusions:

  • Urinary tract infection (UTI) is relatively uncommon after the first month post-pediatric kidney transplantation.
  • Female sex and the presence of a neurogenic bladder are key risk factors for UTI in pediatric kidney transplant recipients.
  • Targeted monitoring and management strategies for these risk factors may improve post-transplant care.
Abstract

More Related Videos

Robot-Assisted Kidney Transplantation07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...