Related Experiment Videos
Sequelae of osteomyelitis variolosa: a case report
Sandeep Nema1, G S Vyas, Sunil Kukreja
1Department of Orthopedics, Gajara Raja Medical College, Gwalior, India.
Rheumatology International
|November 8, 2011
Summary
Osteomyelitis variolosa, a rare complication of smallpox, can lead to severe orthopedic issues like ankle fractures. This case highlights its distinct clinical and radiological features.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Background:
- Osteomyelitis variolosa is a rare osteoarticular complication resulting from smallpox infection.
- It can manifest years after the initial viral illness, presenting as chronic bone inflammation.
Observation:
- A case study of a patient with a history of childhood smallpox infection is presented.
- The patient exhibited an ankle fracture on the affected side, alongside other orthopedic sequelae of smallpox.
Findings:
- The study details the specific clinical presentation of osteomyelitis variolosa in the presented case.
- Key radiological findings characteristic of this condition are discussed, aiding in diagnosis.
Implications:
- Understanding the orthopedic manifestations of osteomyelitis variolosa is crucial for timely diagnosis and management.
- This case underscores the long-term skeletal complications that can arise from viral infections like smallpox.
Related Concept Videos
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.