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[Contaminated small bowel syndrome in infants caused by gram-negative bacteria and yeasts]
H Bodánszky1, K Horváth, H Bin Gadeem
1Semmelweis Orvostudományi Egyetem, Budapest, II. sz. Gyermekklinika.
Insights
Small intestinal bacterial overgrowth (SIBO) occurs when the upper small intestine has too many microbes, causing malabsorption and growth issues in children. Oral antibiotics effectively treat this condition.
Area of Science:
- Pediatric Gastroenterology
- Microbiology
- Digestive Health
Context:
- The upper small intestine is typically sterile in healthy individuals.
- Microbial counts exceeding 10(4)/ml indicate contamination.
- This contamination can lead to significant malabsorption.
Purpose:
- To diagnose small intestinal bacterial overgrowth (SIBO) in children.
- To evaluate the effectiveness of oral antibiotic treatment for SIBO.
Summary:
- Fifty children (1 month to 3 years) were diagnosed with SIBO using breath hydrogen tests and duodenal cultures.
- Growth retardation was a common symptom observed in affected children.
- Oral antibiotics were identified as an effective treatment based on clinical experience.
Impact:
- Highlights the prevalence and consequences of SIBO in pediatric populations.
- Provides evidence for the efficacy of oral antibiotics in managing SIBO.
- Informs clinical practice regarding the diagnosis and treatment of pediatric SIBO.
Abstract:
The upper small intestine is usually "sterile" in a healthy individuals, but due to some reasons the number of microorganisms may reach or increase above 10(4)/ml, leading to the contamination of the small intestine, which may cause severe malabsorption. The authors have diagnosed this syndrome in 50 children, aged between 1 month and 3 years, using breath hydrogen test and duodenal juice culture. Most of these children had growth retardation. According to their experience the authors found that the oral antibiotic is the effective treatment of this syndrome.