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Choroidal thickness in healthy Chinese subjects
Xiaoyan Ding1, Jiaqing Li, Jing Zeng
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Investigative Ophthalmology & Visual Science
|November 8, 2011
Summary
Posterior choroidal thickness varies by location and age. Subfoveal choroidal thickness (SFCT) in healthy individuals over 60 significantly decreases with age, unlike those younger than 60.
Area of Science:
- Ophthalmology
- Anatomy
- Gerontology
Background:
- The posterior choroid's thickness is a key indicator of ocular health.
- Understanding choroidal thickness variations is crucial for diagnosing and managing various eye conditions.
Purpose of the Study:
- To map the posterior choroidal thickness profile in a healthy Chinese population.
- To investigate the relationship between choroidal thickness, age, and refractive error.
Main Methods:
- Enhanced depth imaging spectral-domain optical coherence tomography (EDI-SD-OCT) was used.
- 210 healthy Chinese volunteers (420 eyes) were scanned.
- Subfoveal choroidal thickness (SFCT) and thickness at multiple points around the fovea were measured.
Main Results:
- The choroid was thickest beneath the fovea.
- Temporal choroid was thicker than nasal at 1mm and 3mm from the fovea.
- SFCT showed no correlation with age in individuals under 60, but a significant negative correlation in those over 60.
Conclusions:
- Age significantly impacts posterior choroidal thickness, particularly in individuals over 60.
- SFCT declines by approximately 5.40 μm per year in individuals over 60.
- Age is a critical factor when evaluating choroidal thickness.