Related Experiment Video
Updated: May 27, 2026

09:13
Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment
Published on: April 4, 2017
Photonic Shell-Crosslinked Nanoparticle Probes for Optical Imaging and Monitoring
Nam S Lee1, Guorong Sun, William L Neumann
1Departments of Chemistry and Radiology, Washington University in Saint Louis, Saint Louis, MO 63130 (USA).
Advanced Materials (Deerfield Beach, Fla.)
|November 8, 2011
Abstract:
A pH-insensitive fluorophore is made to give pH-driven responses through its covalent incorporation within a nanostructure derived from pH-responsive polymers. Fluorophore-shell-crosslinked nanoparticles (SCKs) demonstrate notable enhancement of photophysical properties, in the physiological pH region. Fluorophore-SCKs are designed to swell at higher pH and shrink as the pH is lowered, producing high fluorescence vs. low fluorescence outputs, respectively.

