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Updated: May 27, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
3-{[(Benz-yloxy)carbon-yl]amino}-butanoic acid
Abstract:
In the title compound, C(12)H(15)NO(4), the butyric acid group has a stretched trans conformation. The dihedral angle between the phenyl ring and the oxycarb-oxy-amino N-(C=O)-O-C plane is 56.6 (2)°. In the crystal, an inversion dimer is formed by a pair of O-H⋯O hydrogen bonds. The dimers are further linked by N-H⋯O hydrogen bonds between amide groups, forming a tape along the b axis.
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The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
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