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Updated: May 27, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
(E)-2-(3-Cinnamoyl-thio-ureido)acetic acid dimethyl sulfoxide disolvate
Abstract:
In the title compound, C(12)H(12)N(2)O(3)S·2C(2)H(6)OS, the acetic acid and cinnamoyl groups adopt Z and E configurations, respectively, with respect to the thio group about the C-N bonds. The components of the asymmetric unit are connected by N-H⋯O and O-H⋯O hydrogen bonds and in the crystal weak inter-molecular C-H⋯O and C-H⋯S hydrogen bonds further connect the components into chains along the b axis. In the main mol-ecule, an intra-molecular N-H⋯O hydrogen bond is also present.
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