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Related Concept Videos

2° Amines to N-Nitrosamines: Reaction with NaNO201:20

2° Amines to N-Nitrosamines: Reaction with NaNO2

Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview01:26

1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview

Nitrous acid and nitric acids are two types of acids containing nitrogen, among which nitrous acid is weaker than nitric acid. Nitrous acid with a pKa value of 3.37 ionizes in water to give a nitrite ion and the hydronium ion.
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by water loss...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism01:37

1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
Diazonium Group Substitution: –OH and –H01:19

Diazonium Group Substitution: –OH and –H

Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
Electrophilic Aromatic Substitution: Nitration of Benzene01:20

Electrophilic Aromatic Substitution: Nitration of Benzene

The nitration of benzene is an example of an electrophilic aromatic substitution reaction. It involves the formation of a very powerful electrophile, the nitronium ion, which is linear in shape. The reaction occurs through the interaction of two strong acids, sulfuric and nitric acid.
Amines to Sulfonamides: The Hinsberg Test01:23

Amines to Sulfonamides: The Hinsberg Test

The Hinsberg test is a method to identify primary, secondary and tertiary amines, named after its pioneer, Oscar Hinsberg. Here, amines are treated with benzenesulfonyl chloride, also known as the Hinsberg reagent, in the presence of an excess of aqueous base, followed by acidification. Based on the nature of the amines, different changes are observed.
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing sulfonyl...

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4-Sulfamoylanilinium nitrate.

S Pandiarajan, S Balasubramanian, B Ravikumar

    Acta Crystallographica. Section E, Structure Reports Online
    |November 8, 2011
    PubMed
    Summary
    This summary is machine-generated.

    The crystal structure of a novel compound reveals that its positively and negatively charged components form a complex three-dimensional network through hydrogen bonds. This structural arrangement is key to understanding its chemical properties.

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    Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)

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    Area of Science:

    • Crystallography
    • Materials Science
    • Chemical Physics

    Background:

    • Understanding the three-dimensional arrangement of atoms and molecules in crystalline solids is fundamental to predicting their physical and chemical properties.
    • Hydrogen bonding plays a crucial role in molecular self-assembly and the formation of extended networks in solid-state chemistry.

    Purpose of the Study:

    • To elucidate the crystal structure of the title compound, C(6)H(9)N(2)O(2)S(+)·NO(3) (-).
    • To investigate the intermolecular interactions, specifically hydrogen bonding, that govern the assembly of the crystal lattice.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to determine the precise atomic arrangement within the crystal lattice.
    • Analysis of the crystal structure involved identifying hydrogen bond donors and acceptors and characterizing their geometric parameters.

    Main Results:

    • The crystal structure consists of discrete organic cations (C(6)H(9)N(2)O(2)S(+)) and nitrate anions (NO(3)(-)).
    • Cations and anions are interconnected via a network of N-H⋯O hydrogen bonds.
    • These hydrogen bonds link the components into an extended three-dimensional supramolecular architecture.

    Conclusions:

    • The crystal packing is dominated by N-H⋯O hydrogen bonding interactions between the organic cation and the nitrate anion.
    • The observed three-dimensional network structure provides insights into the solid-state behavior and potential applications of this compound.