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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Ethyl 4-chloro-2'-fluoro-3-hy-droxy-5-methyl-biphenyl-2-carboxyl-ate
Acta Crystallographica. Section E, Structure Reports Online
|November 8, 2011
Abstract:
In the title compound, C(16)H(14)ClFO(3), the dihedral angle between the mean planes of the two benzene rings is 71.50 (5)°. Due to an intra-molecular O-H⋯O hydrogen bond between the hy-droxy group and the carbonyl O atom of the ethyl ester group, the ethyl ester group lies within the ring plane. The crystal structure is consolidated by inter-molecular C-H⋯O and C-H⋯F inter-actions.
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