Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

IUPAC Nomenclature of Aldehydes

IUPAC Nomenclature of Aldehydes

Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...

Hydrolysis of Chlorobenzene to Phenol: Dow Process

Hydrolysis of Chlorobenzene to Phenol: Dow Process

Simple aryl halides do not react with nucleophiles under normal conditions. However, the reaction can proceed under drastic conditions involving high temperatures and high pressure to give the substituted products. For example, chlorobenzene is converted to phenol using aqueous sodium hydroxide at 350 °C under high pressure by the Dow process. The reaction follows an elimination-addition mechanism involving a benzyne intermediate. Here, the chloride ion is eliminated to generate the benzyne...

Acidity and Basicity of Alcohols and Phenols

Acidity and Basicity of Alcohols and Phenols

Like water, alcohols are weak acids and bases. This is attributed to the polarization of the O–H bond making the hydrogen partially positive. Moreover, the electron pairs on the oxygen atom of alcohol make it both basic and nucleophilic. Protonation of an alcohol converts hydroxide, a poor leaving group, into water—a good one. The two acid–base equilibria corresponding to ethanol are depicted below.

Nomenclature of Aromatic Compounds with a Single Substituent

Nomenclature of Aromatic Compounds with a Single Substituent

Benzene is the simplest aromatic hydrocarbon or arene. The IUPAC names for simple monosubstituted benzene derivatives are derived by adding the substituent's name as a prefix to the parent benzene. For example, halobenzene, where the halogen could be fluoro (F), chloro (Cl), bromo (Br), and iodo (I).

NMR Spectroscopy of Benzene Derivatives

NMR Spectroscopy of Benzene Derivatives

Simple unsubstituted benzene has six aromatic protons, all chemically equivalent. Therefore, benzene exhibits only a singlet peak at δ 7.3 ppm in the 1H NMR spectrum. The observed shift is far downfield because the aromatic ring current strongly deshields the protons. Any substitution on the benzene ring makes the aromatic protons nonequivalent, and the protons split each other. The peak is, therefore, no longer a singlet and the splitting pattern and their associated coupling constants depend...

Electrophilic Aromatic Substitution: Sulfonation of Benzene

Electrophilic Aromatic Substitution: Sulfonation of Benzene

Sulfonation of benzene is a reaction wherein benzene is treated with fuming sulfuric acid at room temperature to produce benzenesulfonic acid. Fuming sulfuric acid is a mixture of sulfur trioxide and concentrated sulfuric acid.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Erratum to: Fungal oxalic acid inhibits the deamidation of CERK1 ectodomain to dampen chitin-triggered plant immunity.

Science China. Life sciences·2026

Same author

Redesign to Mechanism: Interpretable AI Reveals Determinants of Protein Hydrate Binding.

The journal of physical chemistry letters·2026

Same author

Interpretable Prediction of Mortality Risk in Elderly Patients With Type 2 Diabetes Mellitus and Cerebral Infarction Based on the Medical Information Mart for Intensive Care-Ⅳ Database.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026

Same author

A defense-inducible bidirectional promoter enables disease-resistance engineering in Arabidopsis without growth trade-offs.

Plant physiology·2026

Same author

Entropy-Enabled Site Inversion and Defect Activation in Medium-Entropy Spinels for Near-Black Infrared Emission.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Prevalence, severity, and risk factors for depressive and anxiety symptoms among adolescents: A cross-sectional study.

World journal of psychiatry·2026

Search research articles

Related Experiment Video

Updated: May 27, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

4-(Diphenyl-phosphan-yl)benzoic acid.

Pei-Hua Zhao¹, Fu-Yu Sun, Jun-Jie Liu

¹Research Center for Engineering Technology of Polymeric Composites of Shanxi Province, School of Materials Science and Engineering, North University of China, Taiyuan 030051, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online

|November 8, 2011

Summary

This study details the crystal structure of a novel organic phosphorus compound. Molecular analysis reveals specific dihedral angles and hydrogen bonding patterns in its solid-state arrangement.

More Related Videos

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Published on: October 19, 2017

Related Experiment Videos

Last Updated: May 27, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants

Published on: October 19, 2017

Area of Science:

Crystallography
Organic Chemistry
Materials Science

Background:

Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
Organic phosphorus compounds exhibit diverse applications, necessitating detailed structural characterization.

Purpose of the Study:

To elucidate the crystal structure of the title compound, C(19)H(15)O(2)P.
To analyze the molecular geometry, including dihedral angles between aromatic rings.
To investigate intermolecular interactions, specifically hydrogen bonding, in the crystal lattice.

Main Methods:

Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
Analysis of bond lengths, bond angles, and dihedral angles provided insights into molecular conformation.
The Cambridge Structural Database (CSD) or similar tools were likely used for crystallographic analysis.

Main Results:

The crystal structure of C(19)H(15)O(2)P was successfully determined.
Significant dihedral angles were observed: 75.64° (benzoic acid-phenyl), 80.88° (benzoic acid-phenyl), and 81.35° (phenyl-phenyl).
Inversion dimers formed by O-H⋯O hydrogen bonds between carboxylic acid groups were identified, creating R(2)(2)(8) loops.

Conclusions:

The determined crystal structure provides a fundamental understanding of this organic phosphorus compound's solid-state behavior.
The observed dihedral angles suggest a non-planar molecular conformation.
The hydrogen bonding network plays a significant role in the crystal packing and stability.