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Related Concept Videos

The Pineal Gland01:02

The Pineal Gland

The pineal gland, a diminutive endocrine structure named for its pinecone-shaped appearance, is situated atop the third ventricle within the diencephalon region of the forebrain. This gland, composed of secretory cells known as pinealocytes arranged in compact cords and clusters around dense particles of calcium salts, plays a pivotal role in hormonal regulation.
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Related Experiment Video

Updated: May 27, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
03:13

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Published on: June 28, 2024

Ectopic pineal chordoma.

Eberval G Figueiredo1, Wagner M Tavares, Leonardo Welling

  • 1Division of Neurological Surgery, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil.

Surgical Neurology International
|November 8, 2011
PubMed
Summary

This case highlights a rare pineal region chordoma metastasizing to the peritoneum via a ventriculoperitoneal shunt. It suggests that intradural extraosseous chordomas may arise independently from notochord remnants within the brain.

Keywords:
Chordomametastasisnotochordpineal regionventriculoperitoneal shunt

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Last Updated: May 27, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point
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Area of Science:

  • Neuro-oncology
  • Pathology

Background:

  • Chordomas are rare tumors originating from embryonic notochord remnants.
  • Typically found in sacrococcygeal and clivus regions, they can occur in the neuroaxis.
  • Intradural extraosseous chordomas may represent a distinct entity.

Observation:

  • A unique case of a pineal region chordoma with peritoneal metastasis after a ventriculoperitoneal (VP) shunt procedure is presented.
  • An 18-year-old male with a VP shunt developed abdominal distension and pain.
  • CT scans revealed masses in the pineal and abdominal regions, confirmed as chordoma by histopathology.

Findings:

  • The study presents a rare instance of chordoma metastasis through a VP shunt.
  • Histopathological examination confirmed chordoma in both cranial and abdominal samples.
  • The patient experienced systemic complications and passed away.

Implications:

  • This case supports the hypothesis that notochord remnants can persist within the brain.
  • These remnants may potentially develop into neoplastic lesions, such as chordomas.
  • Understanding the unique behavior of intradural extraosseous chordomas is crucial for diagnosis and management.