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Cases with ruptured membranes that "reseal"
J W Johnson1, R S Egerman, J Moorhead
1Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville.
American Journal of Obstetrics and Gynecology
|September 1, 1990
Summary
Some patients with preterm prepartal rupture of membranes stop leaking amniotic fluid before labor. This "resealing" is associated with better pregnancy outcomes for mother and infant.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
Background:
- Preterm prepartal rupture of membranes (PPROM) is a common obstetric complication.
- A subset of PPROM patients may cease amniotic fluid leakage before labor onset, a phenomenon termed 'resealing'.
Purpose of the Study:
- To investigate the characteristics and obstetric outcomes of patients experiencing PPROM with spontaneous amniotic fluid cessation ('resealing').
Main Methods:
- A case-control study comparing 24 PPROM patients who ceased leaking fluid with matched controls who continued to leak.
- Maternal demographics, obstetric history, ultrasound-assessed amniotic fluid volumes, and neonatal outcomes were analyzed.
Main Results:
- No significant differences in maternal demographics or past obstetric history were found between groups.
- The 'resealing' group had lower amniotic fluid volumes, longer gestation, larger neonates, and reduced neonatal hospitalization and perinatal mortality/morbidity.
- Maternal hospitalization was longer in the 'resealing' group.
Conclusions:
- Spontaneous cessation of amniotic fluid leakage in PPROM ('resealing') is associated with favorable maternal and infant outcomes.
- Aggressive identification and conservative management of 'resealing' cases are recommended.