[Analgesic and anti-inflammatory effects and toxicity of houjianxi]

It is effective for acute and chronic laryngopharyngitis clinically. Houjianxi can raise the pain thresholds during hot-plate test in mice, tail flick test in rats, and writhing test in mice with single dose ig 0.125 to 2.0 g/kg. Houjianxi can also inhibit the swelling of hind paw induced by sc 1% carrageenin 0.1 ml in rats as well as the increased vascular permeability induced by ip 0.7% HAC in mice. Toxic side effects were not observed for Houjianxi ig 48 g/kg x 3 within a day in mice and 1.8 g/kg daily for 90 d in rats.