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Related Experiment Videos

Recurrent alternating stroke.

K S Lee1, H G Bae, I G Yun

  • 1Department of Neurosurgery, Soonchunhyang University Chonan Hospital, Korea.

Journal of Korean Medical Science
|March 1, 1990
PubMed
Summary

Recurrent alternating strokes, involving both ischemic and hemorrhagic events, are rare. This study found that while initial outcomes were favorable, a second alternating stroke often led to severe disability or death.

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Area of Science:

  • Neurology
  • Stroke Medicine
  • Neuroimaging

Background:

  • Recurrent alternating stroke, characterized by sequential ischemic and hemorrhagic events, is an infrequent clinical occurrence.
  • Understanding the patterns and outcomes of such events is crucial for patient management and prognosis.

Observation:

  • A series of eight patients with recurrent alternating strokes diagnosed via CT scans over four years were analyzed.
  • The majority of patients (six) experienced infarcts preceding hemorrhage, while two had hemorrhage first, followed by infarct.
  • All ischemic strokes were lacunar infarcts, and lesions were typically in different locations for each event.

Findings:

  • The mean age of patients at the first and second stroke was 56.6 and 57.5 years, respectively, with an average interval of 11.8 months between events.
  • All patients presented with hypertension.
  • While the first stroke had a favorable outcome for all, the second alternating stroke resulted in moderate to severe disability or death in all patients.

Implications:

  • The study highlights a poor prognosis following a second alternating stroke, emphasizing the need for aggressive risk factor management.
  • Investigating the underlying mechanisms of alternating stroke patterns may reveal novel therapeutic targets.
  • Further research is warranted to elucidate the rarity and specific pathophysiology of recurrent alternating strokes.

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