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Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
(2,6-Difluoro-phen-yl)(4-methyl-piperidin-1-yl)methanone
Acta Crystallographica. Section E, Structure Reports Online
|November 9, 2011
Summary
This study details the molecular structure of a fluorinated organic compound, C(13)H(15)F(2)NO. Researchers observed a chair conformation in the piperidine ring and identified zigzag chains formed by hydrogen bonds in its crystal structure.
Area of Science:
- Organic Chemistry
- Crystallography
- Molecular Structure
Background:
- Understanding the precise three-dimensional arrangement of atoms in organic molecules is crucial for predicting their properties and reactivity.
- Fluorinated organic compounds are of significant interest due to their unique characteristics and diverse applications.
Purpose of the Study:
- To elucidate the detailed molecular structure and crystal packing of the compound C(13)H(15)F(2)NO.
- To investigate the conformational preferences of the piperidine ring and intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the atomic coordinates and unit cell parameters.
- Analysis of the crystal structure included conformational analysis of the piperidine ring and identification of hydrogen bonding networks.
Main Results:
- The piperidine ring in C(13)H(15)F(2)NO adopts a chair conformation.
- A dihedral angle of 48.75(7)° was measured between the piperidine ring and the benzene ring.
- Molecules are interconnected through C-H⋯O hydrogen bonds, forming zigzag chains along the b axis in the crystal structure.
Conclusions:
- The study provides a precise structural characterization of the title compound.
- The observed crystal packing highlights the role of hydrogen bonding in directing the self-assembly of organic molecules.
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