Related Experiment Video

Updated: May 27, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

Redetermination of (E)-3-(anthracen-9-yl)-1-(2-hy-droxy-phen-yl)prop-2-en-1-one

Suchada Chantrapromma, Thawanrat Kobkeatthawin, Kullapa Chanawanno

    Acta Crystallographica. Section E, Structure Reports Online
    |November 9, 2011
    PubMed

    More Related Videos

    A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species08:12

    A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

    Published on: August 16, 2018

    Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions07:12

    Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

    Published on: July 17, 2020

    Related Concept Videos

    Prochirality02:05

    Prochirality

    The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
    E1 Reaction: Stereochemistry and Regiochemistry02:43

    E1 Reaction: Stereochemistry and Regiochemistry

    One of the critical aspects of the E1 reaction mechanism, as also observed in E2, is the regiochemistry, with multiple regioisomers obtained as products. In the example discussed, the presence of water as a weak base favors elimination over substitution to generate two alkenes. Given that alkenes’ stability increases with the number of alkyl groups across the double bond, typically, E1 reactions lead to the Zaitsev product, for this is more substituted and stable than the Hofmann product.
    Preparation of Epoxides03:00

    Preparation of Epoxides

    Overview
    Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
    Epoxidation with Peroxy Acids
    Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy acids to...
    Electrophilic Addition to Alkynes: Hydrohalogenation02:35

    Electrophilic Addition to Alkynes: Hydrohalogenation

    Electrophilic addition of hydrogen halides, HX (X = Cl, Br or I) to alkenes forms alkyl halides as per Markovnikov's rule, where the hydrogen gets added to the less substituted carbon of the double bond. Hydrohalogenation of alkynes takes place in a similar manner, with the first addition of HX forming a vinyl halide and the second giving a geminal dihalide.
    Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene01:17

    Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene

    The electrophilic addition of hydrogen halides such as HBr to alkenes and nonconjugated dienes gives a single product as per Markovnikov’s rule.
    E2 Reaction: Stereochemistry and Regiochemistry02:43

    E2 Reaction: Stereochemistry and Regiochemistry

    Elimination reactions of alkyl halides can yield one or more alkenes depending on the specific regiochemical and stereochemical considerations. While the regiochemistry of the reaction governs the location of the double bond in the product, the stereochemical requirements often influence the geometry.
    When a substrate with two different β hydrogens undergoes an E2 elimination, the presence of a strong base can yield two regioisomeric alkenes. The more-substituted alkene is the major product and...