Related Experiment Video
Updated: May 27, 2026

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
Published on: February 8, 2022
Factors associated with lobar vs. non-lobar intracerebral hemorrhage
H Matsukawa1, M Shinoda, M Fujii
1Department of Neurosurgery, St. Luke's International Hospital, Tokyo, Japan. mahide@luke.or.jp
Objectives:
The relationship between body mass index (BMI) and stroke subtypes has received more research attention than that between BMI and location of intracerebral hemorrhage (ICH). Lobar hemorrhage (LH) differs from non-LH primarily in terms of etiology, i.e. cerebral amyloid angiopathy is the main cause of LH. This study aimed to determine the relationship between BMI and ICH.
Materials And Methods:
In this retrospective study involving 460 consecutive patients with ICH, BMI was significantly lower in LH than for other ICH locations. BMI categories were underweight (BMI < 18.5 kg/m(2)), normal weight (18.5-23.0 kg/m(2)), overweight (23.0-27.5 kg/m(2)), or obesity (≥27.5 kg/m(2)). Outcome at 1 year was evaluated by the modified Rankin Scale (mRS). We investigated the relationship of BMI and other clinical characteristics with LH and non-LH.
Results:
LH was associated with age (>70 years), underweight, unfavorable outcome (mRS ≥3), and daily alcohol consumption. Hypertension and intraventricular bleeding were significantly less common in patients with LH than those with non-LH.
Conclusions:
Alongside risk factors conventionally thought to be related to LH, underweight may also be a LH-related factor, specifically in the elderly.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Lateralization
Stroke: Introduction and Types
