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Published on: October 24, 2019

Kawasaki disease in Jordan: demographics, presentation, and outcome

Iyad Al-Ammouri1, Shorouk Al-Wahsh, Najwa Khuri-Bulos

  • 1Department of Pediatrics, University of Jordan, Jordan University Hospital, Amman, Jordan. Iyad72@hotmail.com

Cardiology in the Young
|November 10, 2011
PubMed

Insights

Kawasaki disease, a cause of pediatric coronary artery issues, shows high cardiac involvement in Jordan. Younger age predicts coronary artery problems in children with this condition.

Area of Science:

  • Pediatrics
  • Cardiology
  • Epidemiology

Background:

  • Kawasaki disease is the primary cause of acquired coronary artery disease in children.
  • Limited data exists on Kawasaki disease's impact on coronary arteries in Jordan and developing nations.

Purpose of the Study:

  • To analyze clinical and demographic data of Kawasaki disease patients in Jordan.
  • To determine the incidence and predictors of cardiac involvement, specifically coronary artery abnormalities, in pediatric patients.

Main Methods:

  • Retrospective review of medical records for 34 Kawasaki disease patients (1997-2010).
  • Analysis of echocardiographic and angiographic data at presentation and follow-up.
  • Statistical analysis to identify variables associated with coronary artery involvement.

Main Results:

  • The median age of presentation was 19 months, with a 3.9:1 male to female ratio.
  • Coronary artery involvement was observed in 41% of patients, including aneurysms (20.5%) and ectasia (20.5%).
  • Younger age was the sole independent predictor of coronary involvement (OR 0.63 per year).

Conclusions:

  • Kawasaki disease presents a significant risk for coronary artery abnormalities in Jordanian children.
  • Early diagnosis and monitoring are crucial, particularly in younger children.
  • Further research is needed to understand long-term outcomes in developing countries.

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