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FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update

Ian T Flockhart1, Matthew Booker, Yanhui Hu

  • 1Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

Nucleic Acids Research
|November 10, 2011
PubMed

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...