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Haemophilus aphrophilus endocarditis.

C H Webb1, G M Hogg

  • 1Department of Bacteriology, Royal Victoria Hospital, Belfast.

The British Journal of Clinical Practice
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

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Haemophilus aphrophilus endocarditis can affect heart valves in children with congenital heart disease. Prolonged antibiotic treatment, including ampicillin and gentamicin, is crucial for successful treatment, as short courses may be insufficient.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Microbiology

Background:

  • Congenital heart disease (CHD) predisposes patients to infective endocarditis.
  • Haemophilus aphrophilus is a rare cause of endocarditis, particularly in pediatric patients with CHD.
  • Dental procedures can be a source of bacteremia, increasing endocarditis risk.

Observation:

  • A pediatric case of Haemophilus aphrophilus endocarditis affecting the mitral and tricuspid valves is presented.
  • The patient had underlying congenital heart disease and underwent dental treatment without antibiotic prophylaxis.
  • Clinical presentation included signs and symptoms consistent with infective endocarditis.

Findings:

  • Infective endocarditis was confirmed, with Haemophilus aphrophilus identified as the causative pathogen.

Related Experiment Videos

  • The infection involved both the mitral and tricuspid valves, indicating significant valvular damage.
  • Treatment required a prolonged course of high-dose ampicillin in combination with gentamicin.

    • Implications:

    • This case highlights the importance of antibiotic prophylaxis for dental procedures in patients with CHD.
    • Extended and combination antibiotic therapy may be necessary for successful treatment of Haemophilus aphrophilus endocarditis.
    • Understanding the specific antimicrobial susceptibilities and treatment durations is critical for managing rare forms of infective endocarditis.