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Updated: May 27, 2026

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
Published on: November 30, 2021
Fat necrosis of the newborn--report on two cases
Ana Cristina Santos Oliveira1, Manuela Selores, Olga Pereira
1Serviço de Dermatologia, Hospital de Santo António, Centro Hospitalar do Porto, Porto, Portugal. anacsoliveira@gmail.com
Abstract:
Subcutaneous fat necrosis of the newborn is an uncommon disorder occurring during the prenatal stage. Generally occurring in full-term neonates or during the first four weeks after a traumatic delivery, the disorder is characterized by the appearance of hard subcutaneous nodules or plaques on the trunk, buttocks or thighs. It is normally a benign and transient condition, although it may be complicated by hypocalcemia, which requires close monitoring until skin lesions are cured. The authors describe two cases of subcutaneous fat necrosis of the newborn, one occurring in a full-term neonate and the other in a premature newborn, both related to traumatic delivery and fetal distress.
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