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Updated: May 27, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
[Ocular findings in children with congenital toxoplasmosis]
Janer Aparecida Silveira Soares1, Luciano Sólia Násser, Sílvio Fernando Guimarães Carvalho
1Department of Pediatrics, Universidade Estadual de Montes Claros, MG, Brazil.
Insights
Congenital toxoplasmosis frequently causes ocular issues like retinochoroiditis and strabismus in infants. Early detection and management are crucial for affected children.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pediatrics
Context:
- Congenital toxoplasmosis is a significant concern in pediatric infectious diseases.
- Ocular manifestations can be severe and impact long-term vision.
- Understanding common ocular findings aids in early diagnosis and management.
Purpose:
- To identify the most frequent ocular complications in infants diagnosed with congenital toxoplasmosis.
- To analyze the prevalence and characteristics of eye lesions in this population.
Summary:
- A retrospective study evaluated 58 children with congenital toxoplasmosis.
- Ocular lesions were present in 34 eyes of 20 children (34.5%).
- Retinochoroiditis (100%) and strabismus (70%) were the most common findings, often affecting the posterior pole and macula.
Impact:
- Retinochoroiditis and strabismus are significant sequelae of congenital toxoplasmosis.
- Findings highlight the importance of ophthalmologic evaluation in newborns with suspected congenital toxoplasmosis.
- Early identification of these ocular issues can guide timely interventions and improve outcomes.
Purpose:
This study aimed to know the most common ocular findings in children with congenital toxoplasmosis.
Methods:
This is a retrospective study carried out from a historical cohort, with a quantitative approach. We evaluated children referred to a pediatric infectious disease service and included only those with confirmed diagnosis of congenital toxoplasmosis. The ophthalmologic evaluation included regular fundus examination under pupil dilation.
Results:
Of 58 children presumably exposed to risk of the disease during the pregnancy, 20 had ocular lesions during the first year of life (34 eyes). Of these, 12 were asymptomatic at birth. Strabismus was noted in 14 children (70%). In one child there was ptosis, and another had decrease in the palpebral fissure (microphthalmia). Retinochoroiditis was the most common complication, present in all 20 children. Seven children (35%) showed unilateral changes and 13 children showed bilateral changes (65%), with emphasis on the location in the posterior pole and macula.
Conclusion:
Retinochoroiditis and strabismus were outstanding as important sequelae of congenital toxoplasmosis.
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