Normative data for anthropometric parameters used in delineation of dysmorphic features in north Indian children

Seema Kapoor1, Shanti Bhuhsan, Vidya B Ghosh

  • 1Department of Pediatrics, Maulana Azad Medical College, New Delhi 110002, India. drseemakapoor@gmail.com

Insights

This study provides crucial normative anthropometric data for Indian infants and children up to two years old. These measurements aid in identifying dysmorphic features and potential anomalies, emphasizing the need for ethnic-specific data.

Area of Science:

  • Pediatric anthropometry
  • Clinical genetics
  • Dysmorphic feature assessment

Background:

  • Accurate anthropometric data is essential for identifying dysmorphic features in children.
  • Existing normative data may not be representative of diverse ethnic populations.
  • Establishing regional ethnic data is critical for precise clinical evaluations.

Purpose of the Study:

  • To establish normative data for key anthropometric parameters in Indian infants and children up to two years of age.
  • To facilitate the delineation of dysmorphic features using reliable, age- and ethnicity-specific measurements.
  • To develop percentile curves for commonly used anthropometric parameters.

Main Methods:

  • A cross-sectional observational study involving 600 infants and children aged 0-24 months.
  • Measurement of seven anthropometric parameters: inner and outer intercanthal distance, interpupillary distance, ear length, internipple distance, hand length, and middle finger length.
  • Data analysis using the LMS method to generate percentile curves for each age group.

Main Results:

  • No statistically significant sex-based differences were observed in the measured parameters.
  • Significant differences were noted when compared to South East Asian and Caucasian populations, highlighting the need for regional data.
  • Prevalence of isolated anomalies such as polydactyly, syndactyly, preauricular tags, and paraumbilical hernia were documented.

Conclusions:

  • Normative data specific to ethnic origin is valuable for charting dysmorphic traits.
  • Parameters falling below the 3rd or above the 97th percentile warrant further evaluation for co-existing anomalies.
  • The generated percentile charts may have applicability across India, pending further validation studies.
Abstract

Related Concept Videos

Variation: Normal Distribution, Range, and Standard Deviation02:32

Variation: Normal Distribution, Range, and Standard Deviation

In the field of psychology, there are several ways to organize measurements of a trait, feature, or characteristic (i.e., variables). Qualitative data, such as ethnicity, can be tabulated into a frequency count to provide information about the proportion, as well as the variety of groups in a sample or population. On the other hand, researchers can perform a wider set of calculations on quantitative data. The mean, mode, and median, for instance, are central tendency measures to identify a...
Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Signs of Puberty01:27

Signs of Puberty

Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Applications of Normal Distribution01:22

Applications of Normal Distribution

The normal distribution is a useful statistical tool. One of its practical applications is determining the door height after considering the normal distribution of heights of persons, such that many can pass through it easily without striking their heads. The normal distribution can also determine the probability of a person having a height less than a specific height.
The heights of 15 to 18-year-old males from Chile from 1984 to 1985 followed a normal distribution. The mean height is 172.36...