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Monoclonal antibody therapies against anthrax

Zhaochun Chen1, Mahtab Moayeri, Robert Purcell

  • 1Laboratory of Infectious Diseases National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. zchen@niaid.nih.gov

Toxins
|November 10, 2011
PubMed
Summary

Monoclonal antibodies targeting Bacillus anthracis virulence factors, including toxins and capsule, are crucial for anthrax treatment. A combination therapy of these antibodies may offer enhanced therapeutic benefits against anthrax.

Keywords:
Bacillus anthracisa cocktail of mAbsanti-EF mAbsanti-LF mAbsanti-PA mAbsanti-capsule mAbspost-exposure treatment of anthrax

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