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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...

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Related Experiment Video

Updated: May 27, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
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Published on: November 21, 2013

Addressing non-adherence to antipsychotic medication: a harm-reduction approach.

M A Aldridge1

  • 1Early Interventions Unit, South London and Maudsley NHS Foundation Trust, London, UK. matthew.aldridge@slam.nhs.uk

Journal of Psychiatric and Mental Health Nursing
|November 11, 2011
PubMed
Summary

This study explores harm-reduction interventions for antipsychotic non-adherence. It focuses on patient choice and minimizing withdrawal risks, offering a collaborative approach to improve medication adherence.

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Area of Science:

  • Psychiatry
  • Pharmacology
  • Mental Health Interventions

Background:

  • Non-adherence to antipsychotic medications is a significant challenge in mental health treatment.
  • Existing interventions often focus on compliance rather than patient autonomy.
  • Antipsychotic withdrawal can lead to adverse health outcomes and relapse.

Observation:

  • This paper examines the evidence for interventions targeting non-adherence to antipsychotics.
  • A case study illustrates collaborative adherence improvement strategies.
  • The principles of harm reduction are applied to mental health care.

Findings:

  • A planned non-adherence harm-reduction intervention is proposed.
  • This intervention respects patient choice and learning from experience.
  • It aims to mitigate the risks associated with antipsychotic withdrawal.

Implications:

  • Harm reduction offers a patient-centered framework for managing antipsychotic non-adherence.
  • Collaborative interventions can empower patients and improve treatment outcomes.
  • Further evaluation of this intervention method is warranted.