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Updated: May 27, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
Proposed clinical classification for oral submucous fibrosis
Chandramani B More1, Sunanda Das, Hetul Patel
1Department of Oral Medicine & Radiology, K.M. Shah Dental College & Hospital, Sumandeep Vidyapeeth University, Piparia, Vadodara 391760, Gujarat, India. drchandramanimore@rediffmail.com
Abstract:
Oral Submucous Fibrosis (OSMF) is a chronic, progressive, scarring disease, that predominantly affects people of South Asia and South-East Asia, where chewing of arecanut and its commercial preparation is high. Presence of fibrous bands is the main characteristic feature of OSMF. Based on clinical and/or histopathological features of OSMF, various classifications have been put forth till date. But the advantages and drawbacks of these classification supersedes each other, leading to perplexity. Our various studies and clinical experience in the field of OSMF have initiated us to propose/introduce the new clinical classification which could assist the clinician in the categorization of this potentially malignant disorder according to its biological behaviour and hence its subsequent medical and surgical management.
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