Focal epithelial hyperplasia: Case report

Area of Science:

• Oral pathology
• Dermatology
• Virology

Background:

• Focal epithelial hyperplasia (FEH) is a benign oral mucosal condition.
• It is associated with specific human papilloma virus (HPV) genotypes.
• FEH is rare, particularly in certain geographic or demographic groups.

Observation:

• A case study of a 15-year-old patient presenting with FEH is detailed.
• The patient had no history of sexual contact or HIV infection.
• The oral lesion exhibited characteristic histopathological findings.

Findings:

• Histopathological examination revealed acanthosis and parakeratosis, consistent with FEH.
• The etiology in this case was presumed to be environmental transmission of HPV.
• This challenges typical transmission route assumptions for oral HPV lesions.

Implications:

• Highlights the possibility of non-sexual HPV transmission in oral lesions.
• Emphasizes the importance of considering environmental factors in HPV etiology.
• Contributes to understanding the epidemiology and transmission of focal epithelial hyperplasia.