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Updated: May 27, 2026
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Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
Preparation of encapsulated alliinase in alginate microparticles
1School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Korea.
Biotechnology Letters
|November 11, 2011
Abstract:
Alliinase (alkylsulphenate lyase, EC 4.4.1.4), which catalyses the production of allicin, was immobilized in alginate microparticles. Addition of pyridoxal 5'-phosphate to the microparticles enhanced alliinase activity. Encapsulated alliinase were significantly higher (30 and 22%, respectively) than those of non-encapsulated alliinase at 60°C and at pH 2. Therefore, microencapsulation of alliinase with alginate can offer an effective way of sustaining enzyme activity during oral administration and passage through the stomach.
