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Updated: May 27, 2026

Quantitative Atomic-Site Analysis of Functional Dopants/Point Defects in Crystalline Materials by Electron-Channeling-Enhanced Microanalysis
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Count-Rate Performance of the Discovery STE PET Scanner Using Partial Collimation.

Lawrence R Macdonald1, Ruth E Schmitz, Adam M Alessio

  • 1Department of Radiology, University of Washington, Seattle, WA 98195 USA (telephone: 206-543-3653).

IEEE Nuclear Science Symposium Conference Record. Nuclear Science Symposium
|November 11, 2011
PubMed
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Partial collimation in PET scanners, by removing septa, enhances noise equivalent count-rates (NEC) over standard 2D and 3D methods. This technique shows promise for optimizing clinical PET imaging performance.

Area of Science:

  • Nuclear Medicine
  • Medical Imaging Physics

Background:

  • Conventional 2D and 3D Positron Emission Tomography (PET) imaging face limitations in noise equivalent count-rates (NEC) at clinically relevant activity concentrations.
  • Improving NEC is crucial for enhanced image quality and reduced scan times in clinical PET applications.

Purpose of the Study:

  • To investigate the efficacy of partial collimation, specifically removing septa from conventional 2D collimators, to improve NEC in clinical PET scanners.
  • To evaluate two partial collimation configurations: 2.5D (half septa removed) and 2.7D (two-thirds septa removed).

Main Methods:

  • System performance was modeled using the SimSET simulation package.
  • Measurements were conducted using NEMA NU2-2001 standard phantoms (20 cm diameter, 70 cm length) and larger cylinders (27 cm and 35 cm diameter).

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  • Image quality was assessed using a dedicated phantom with the 2.7D collimator configuration, employing custom 2.7D normalization for reconstruction.

    • Main Results:

    • SimSET simulations accurately predicted the relative NEC curves, which were validated by experimental measurements.
    • Both 2.5D and 2.7D partial collimation demonstrated higher NEC compared to conventional 2D and 3D methods within the ~5-20 mCi activity range.
    • Successful image reconstruction of the image quality phantom was achieved using the 2.7D data and custom normalization.

    Conclusions:

    • Partial collimation, by strategically removing septa, offers a viable strategy to enhance NEC in fixed-collimator PET systems.
    • This approach shows significant potential for optimizing clinical PET imaging, leading to improved diagnostic accuracy and efficiency.