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Related Concept Videos

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Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

Updated: May 27, 2026

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
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Published on: February 27, 2019

Antitumor peptides from marine organisms.

Lan-Hong Zheng1, Yue-Jun Wang1, Jun Sheng1

  • 1Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.

Marine Drugs
|November 11, 2011
PubMed
Summary

Marine organisms offer a vast source of novel antitumor peptides. This review details their biological properties, molecular diversity, and mechanisms, highlighting potential cancer therapies.

Keywords:
antitumormarine organismspeptides

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Area of Science:

  • Marine Biology
  • Pharmacology
  • Biochemistry

Background:

  • Marine biodiversity represents a rich source of novel bioactive compounds.
  • Marine-derived bioactive substances are increasingly explored for therapeutic applications, particularly in oncology.
  • Peptides isolated from marine organisms show significant potential as anticancer agents.

Purpose of the Study:

  • To review the progress in the study of antitumor peptides derived from marine sources.
  • To describe the biological properties and mechanisms of action of various marine peptides.
  • To present the molecular diversity and pharmacological properties of novel marine antitumor peptides.

Main Methods:

  • Literature review of studies on marine-derived antitumor peptides.
  • Analysis of biological activities, including induction of apoptosis, effects on tubulin-microtubule dynamics, and angiogenesis inhibition.
  • Compilation of data on molecular diversity and pharmacological characteristics.

Main Results:

  • Marine peptides exhibit diverse mechanisms against cancer, including apoptosis induction, disruption of microtubule formation, and anti-angiogenic effects.
  • Significant molecular diversity exists among marine antitumor peptides, offering a wide range of structural and functional possibilities.
  • Several novel marine peptides demonstrate promising pharmacological properties for cancer treatment.

Conclusions:

  • Marine-derived peptides are a valuable resource for the discovery of new anticancer drugs.
  • Further research into marine bioactive substances can lead to the development of effective antitumor agents.
  • Understanding the mechanisms of action and molecular diversity of these peptides is crucial for advancing marine-based cancer therapy.