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Updated: May 27, 2026

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution
Published on: April 16, 2019
[Management of acute alcoholic steatohepatitis]
Fabienne Groebli1, Laurent Spahr, Nicolas Garin
1Service de médecine interne générale, Département de médecine interne, de réhabilitation et de gériatrie, HUG, 1211 Genève 14. Fabienne.Groebli@hcuge.ch
Abstract:
Alcoholic steatohepatitis is an acute inflammatory liver disorder that often complicates the course of underlying cirrhosis. Severe alcoholic steatohepatitis, defined as a Maddrey's discriminant function greater than 32 or association with hepatic encephalopathy, carries a high short-term mortality that is significantly reduced by corticosteroids. A comprehensive work-up is necessary for the presence of concomitant infection or associated viral hepatitis. A liver biopsy must be performed to confirm the diagnosis prior to initiation of steroids. This article summarizes the management of alcoholic steatohepatitis.
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