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Updated: May 27, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
[Chromosomal translocations in soft tissue sarcomas: from molecular biology to clinical application]
J Roma1, A Masià, A Almazán-Moga
1Grupo de Investigación translacional en el cáncer del niño, Institut de Recerca, Vall d'Hebron, Barcelona, España.
Abstract:
Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.

