Pretrial EEG coherence as a predictor of semantic priming effects

Twenty subjects were presented 240 randomized trials of a lexical decision task (LDT) while connected to a 16-electrode EEG montage. EEG data were acquired for 2 sec prior to the onset of each LDT trial. Alpha (9-13 Hz) coherence, alpha power, and 3- to 30-Hz power from five different combinations of EEG electrodes were used to predict semantic effects in the LDT trials. High pretrial coherence in the Right Hemisphere and Left Posterior-Parietal regions was associated with greater semantic facilitation (faster reaction times) in related-prime trials and greater semantic inhibition (slower reaction times) in unrelated-prime trials, relative to neutral-prime trials. No power variables were associated with semantic effects. Results support an information flow model of the functional significance of EEG coherence to cognitive processing.