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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Health consequences of obesity
1The Tulane Center for Cardiovascular Health, Tulane University Health Sciences Center, New Orleans, Louisiana, USA. berenson@tulane.edu
Insights
Childhood cardiovascular risk factors, such as obesity, predict adult heart disease and early death. Early identification and intervention are crucial for preventing lifelong cardiovascular disease and mortality.
Area of Science:
- Public Health
- Epidemiology
- Cardiology
Background:
- Cardiovascular diseases are the leading cause of death globally, surpassing other causes.
- Cardiovascular risk factors are identifiable in childhood and predict adult cardiac risk.
- Childhood obesity is a significant contributor to the global burden of heart disease.
Purpose of the Study:
- To highlight the significance of childhood cardiovascular risk factors.
- To emphasize the link between childhood risk factors and adult cardiovascular outcomes.
- To underscore the importance of early life perspectives in understanding cardiovascular disease.
Main Methods:
- Long-term epidemiologic studies in youth.
- Analysis of childhood risk factors, including obesity.
- Review of established literature and landmark studies like the Bogalusa Heart Study.
Main Results:
- Childhood cardiovascular risk factors are established and identifiable.
- These childhood factors predict adult cardiac risk and premature mortality.
- Heart disease, driven by factors like childhood obesity, is a major global cause of death.
Conclusions:
- Adult heart disease has its origins in childhood.
- Early identification of cardiovascular risk factors in children is critical.
- Addressing childhood obesity and other risk factors can mitigate future cardiovascular disease burden.
Abstract:
Epidemiologic studies have established that cardiovascular (CV) risk factors including obesity are identifiable in childhood. Childhood risk factors are predictive of adult cardiac risk and even premature death [Franks et al. (2010) N Engl J Med 362:485-493]. In the United States, CV diseases remains the leading causes of death. In fact, heart disease has become the major cause of death worldwide, surpassing undernutrition and infectious diseases, largely related to obesity in childhood [Wang and Lobstein (2006) Int J Pediatr Obes 1:11-25]. The concept that adult heart diseases begin in childhood is an outgrowth of extensive long-term epidemiologic studies in youth, that is, the Bogalusa Heart Study [Berenson et al. (1986) Causation of cardiovascular risk factors in children: Perspectives on cardiovascular risk in early life, Raven Press Books Ltd].
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