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Updated: May 27, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Community-acquired methicillin-resistant Staphylococcus aureus infections requiring admission to a Tunisian pediatric
Khaled Menif1, Asma Bouziri, Ammar Khaldi
1Pediatric Intensive Care Unit, Children's Hospital of Tunis, Tunisia.
Insights
Severe community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections in children are rare but serious. This study reviews 14 pediatric intensive care unit cases, finding pneumonia and septic shock common, with lower mortality than previously reported.
Area of Science:
- Pediatric Infectious Diseases
- Intensive Care Medicine
- Microbiology
Background:
- Limited literature exists on severe community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in pediatric intensive care units.
- CA-MRSA is a significant pathogen in community-acquired infections.
Purpose of the Study:
- To describe the clinical features and outcomes of children with CA-MRSA admitted to a Tunisian pediatric intensive care unit.
- To assess the presentation and severity of CA-MRSA infections in a pediatric intensive care setting.
Main Methods:
- Retrospective chart review of patients diagnosed with CA-MRSA over a 10-year period.
- Analysis of clinical data, including patient demographics, clinical presentation, and outcomes.
Main Results:
- Fourteen cases of severe CA-MRSA were identified, representing 0.32% of admissions.
- Pulmonary involvement was universal, with 42.8% experiencing septic shock and 14.3% developing deep venous thrombosis.
- The mortality rate was 14.3%.
Conclusions:
- Severe CA-MRSA pneumonia was the predominant clinical presentation in this cohort.
- The observed mortality rate for CA-MRSA infection in this series is lower than previously reported in the literature.
Background:
There is limited literature describing severe community acquired methicillin-resistant S aureus (CA-MRSA) in children admitted to an intensive care unit.
Aim:
To review clinical features and outcome of children admitted in a Tunisian pediatric intensive care with CA-MRSA.
Methods:
Retrospective chart review of patients coded for CAMRSA over 10 years.
Results:
There were 14 (0.32% of all admissions) patients identified with severe CA-MRSA. The median age was 3 months (range,0.5-156 months). All patients had pulmonary involvement. Six children (42.8%) developed septic shock. Two (14.3%) patients had multifocal infection with deep venous thrombosis. Two (14.3%) patients died.
Conclusion:
Severe CA-MRSA pneumonia dominated presentation. The mortality of CA-MRSA infection in our series is lower than reported in the literature.
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