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[The determination of ketamine in biological fluids]
P Kintz1, P Mangin, A A Lugnier
1Institut de Médecine Légale, Strasbourg.
Cahiers D'Anesthesiologie
|May 1, 1990
Abstract:
A method for the identification and quantification of ketamine in biological fluids by GC/NPD is presented. The procedure employs SKF 525 A as the internal standard and requires no derivatization. After a single-step extraction, analysis is achieved in 5 min. The lower limit of detection was found to be 1 microgram/1 for ketamine in plasma. This method appears to be rapid, sensitive and applicable to forensic and clinical toxicological analyses.