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Dendritic cell lineage commitment is instructed by distinct cytokine signals

Kristin M Seré1, Qiong Lin, Piritta Felker

  • 1Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany. kristin.sere@rwth-aachen.de

European Journal of Cell Biology
|November 15, 2011
PubMed
Summary

Cytokine signaling, including gp130, GM-CSF, and TGF-β1, differentially regulates dendritic cell (DC) development. Inflammatory signals like GM-CSF promote inflammatory DC differentiation, while TGF-β1

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