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Tackling the legs of mannan-binding lectin

Erhard Hohenester1

  • 1Department of Life Sciences, Imperial College London, London SW7 2AZ, UK. e.hohenester@imperial.ac.uk

Structure (London, England : 1993)
|November 15, 2011
PubMed

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Selectins01:25

Selectins

Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain, which...